Target Trial Emulation brings the logic of randomized trials into real-world data
Target Trial Emulation does not replace randomized controlled trials, but it applies their logic and rigor to real-world data analysis.
The Nordics offer a unique environment for healthcare research and data utilisation. With Medaffcon, international partners – such as pharmaceutical companies – can make use of this environment effectively, systematically, and successfully.
The Nordic countries are known for their high-quality healthcare, systematic registries, and strong research infrastructure. Pharma and technology companies can greatly benefit from these, but navigating the national processes, from data access applications to analysis, requires deep local expertise and an understanding of each country’s health-data infrastructure.
Access to the right data is critical for successful research and this is Medaffcon’s core expertise.
Medaffcon has strong Real-World Evidence (RWE) expertise, established processes for data collection, and specialists based in both Finland and Sweden. Medaffcon also has deep knowledge of each Nordic country’s ethical practices, legal frameworks, and research infrastructures.
Medaffcon’s Scientific Advisor, Johan Rehnberg, is involved in multiple projects across the Nordic countries. These projects are always carried out in collaboration with experts from respective country. According to Rehnberg, Medaffcon specialists know how to design and execute data collection processes that account for the specific features of each country, such as data accessibility, registry structures, and approval procedures.
“A Nordic approach to data collection carried out through Medaffcon saves clients’ resources, reduces duplicate work, and accelerates processes. Clients don’t need to establish separate projects in each country, as Medaffcon provides a Nordic approach to collecting and analysing information from multiple countries,” Rehnberg explains.
High-quality data collected in one Nordic country can often provide valuable insights for the entire region. However, combining data from two or more countries further strengthens the generalisability of results. This supports research and development in many ways, since healthcare systems, patient profiles, and disease prevalence are partly similar across the region.
Target Trial Emulation does not replace randomized controlled trials, but it applies their logic and rigor to real-world data analysis.
The data team keeps Medaffcon's research projects on track and ensures that the research findings are scientifically sound. At the heart of the team’s work is the processing and analysis of patient data, particularly in Real-World Evidence (RWE) studies.
Medaffcon's European Lung Cancer Congress (ELCC) poster showcased key findings from a recent study on non-small cell lung cancer (NSCLC).
Scientific Advisor
PhD
Johan joined Medaffcon in August 2024. He holds a PhD in Public Health and in 2023 he completed a four-year postdoctoral research position at Karolinska Institutet, where he led an international research project in collaboration with researchers from Amsterdam University Medical Center (UMC).
In 2023, Johan transitioned from academia to a role as a medical assessor at the Swedish Dental and Pharmaceutical Benefits Agency (TLV), where he gained valuable insights into the processes involved in bringing pharmaceutical products to the Swedish market.
Johan’s strengths lie in his decade-long research experience within multidisciplinary environments at both Karolinska Institutet and Stockholm University. He has extensive experience working with Swedish and Nordic health register data, which, combined with his regulatory knowledge from TLV, makes him well-equipped for planning and conducting RWE studies in Sweden.
“I am excited to continue leveraging the high-quality health registers available in the Nordics to generate valuable insights. These insights will empower patients, healthcare providers, and pharmaceutical companies to make more informed, evidence-based decisions.”