Discussions on Fair Pricing of Medicines at the Swedish Health Economics Days
The Swedish Health Economics Association (SHEA) held its annual conference, offering valuable insights into key topics in health economics.
In healthcare, there is a vast amount of data being generated and processed. Sometimes, its utilization is cumbersome because the data is scattered, and its analysis requires a lot of preprocessing. The OMOP data model (Observational Medical Outcomes Partnership) seeks to address this challenge. In Finland, the utilization of OMOP was explored in a pilot study, in which Medaffcon also participated.
The Observational Health Data Sciences and Informatics (OHDSI) organization drives the utilization of the OMOP data model. OMOP standardizes healthcare data and enables the uniform processing of data from various sources.
“The use of the OMOP data model would significantly accelerate projects by streamlining the preprocessing of the data. Currently, preprocessing takes up to half of the working hours in research projects, sometimes exceeding half of the total time. When the data is in a consistent format, creating reusable analysis codes and conducting reproducible studies becomes more straightforward. Also, the open source nature of the data model simplifies leveraging artificial intelligence for querying and analyzing the data.”, says Medaffcon’s Sr. Data Scientist Juhani Aakko.
One of the benefits of the OMOP (The Observational Medical Outcomes Partnership) data model is that studies could be more easily conducted across different hospitals and countries. Authorities would also benefit from smoother data utilization.
In Finland, the utilization of the OMOP (Observational Medical Outcomes Partnership) data model has been tested in three university hospitals, HUS (Helsinki University Hospital), the Pirkanmaa and Varsinais-Suomi Wellbeing Services County and Fimea (The Finnish Medicines Agency) in a pilot project funded by Sitra (The Future Fund).
In the pilot, Fimea (The Finnish Medicines Agency) defined the information needs related to the use of new medications. University hospitals evaluated whether these information needs could be met by utilizing the hospital OMOP (The Observational Medical Outcomes Partnership) databases to extract the necessary information and to produce the aggregated results.
The pilot examined three different use cases related to the treatment of SMA (spinal muscular atrophy) and multiple myeloma, as well as the use of CART therapies (CAR T-cell therapies). The goal was to assess the suitability of the piloted model for practical use. Medaffcon conducted the technical implementation based on data from Helsinki University Hospital for the questions related to the treatment of multiple myeloma and the use of CART therapies.
“We analyzed data from the OMOP (The Observational Medical Outcomes Partnership) database and assessed whether it could answer the research questions and conducted the analysis. The analysis codes were shared with the collaborators from Pirkanmaa (PIRHA) and Varsinais-Suomi (VARHA) Wellbeing Services County who could then perform the same analysis easily from their OMOP databases.”, Medaffcon’s Sr. Data Scientist Juhani Aakko says.
Juhani Aakko considers the OMOP (The Observational Medical Outcomes Partnership) data model as an important step towards better utilization of healthcare data. Its broader usage would support healthcare organizations in research and data-driven decision-making, as well as authorities and pharmaceutical companies in utilizing health data to support patients’ better and impactful treatment.
Medaffcon, founded in 2009, is a Nordic research and consulting company specializing in Real-World Evidence, Medical Affairs, and Market Access. With offices in Stockholm, Sweden, and Espoo, Finland, we provide expert services across the Nordic region. Our services combine strong medical and health economic expertise with modern data science.
The company employs some 30 experts. Since 2017, Medaffcon has been a subsidiary of Tamro Oyj and is part of the PHOENIX group, which is a leading provider of healthcare services in Europe.
The Swedish Health Economics Association (SHEA) held its annual conference, offering valuable insights into key topics in health economics.
Target Trial Emulation does not replace randomized controlled trials, but it applies their logic and rigor to real-world data analysis.
The data team keeps Medaffcon's research projects on track and ensures that the research findings are scientifically sound. At the heart of the team’s work is the processing and analysis of patient data, particularly in Real-World Evidence (RWE) studies.
Sr. Data Scientist
D.Sc. (Tech.)
Juhani joined Medaffcon in October 2020 as a data scientist. Prior to joining Medaffcon, Juhani has worked as a data scientist in a global IT company as well as a scientist at the University of Turku in the Medical Bioinformatics Centre (MBC) and Functional Foods Forum (FFF). Juhani holds a Doctor of Science in Technology degree (2017) and the topic of his thesis was the development of human gut microbiota in early infancy.
Juhani has experience from applying statistical and machine learning methods in medicine and due to his multidisciplinary background, he can easily communicate with people with varied expertise ranging from clinicians to IT-professionals. “Knowledge management and business intelligence have become hot topics also in the social and healthcare sectors. It is very interesting to be involved in harnessing the vast amounts of data available in the systems to actual usable information to support decision making. Both traditional statistics as well as advanced analytics and artificial intelligence will be in a key role in this job.”